Table 2.
Results of logistic regression analysis for the influence factors of GER-s and GER-d.
| Univariable logistic regression | Multivariable logistic regression | |||
| Variables | OR (95% CI) | P value | OR (95% CI) | P value |
| Age (yr) | 1.027 (1.012–1.042) | <.001∗ | – | |
| Sex | ||||
| Female | 1.0 (reference) | 1.0 (reference) | ||
| Male | 4.500 (3.283–6.167) | <.001∗ | 2.070 (1.415, 3.026) | <.001∗ |
| BMI | ||||
| Normal (<25 kg/m2) | 1.0 (reference) | – | ||
| Overweight (25–30 kg/m2) | 3.078 (2.184–4.340) | <.001∗ | – | |
| Obese (>30 kg/m2) | 3.927 (1.823–8.458) | <.001∗ | – | |
| Smoking | 2.467 (1.770–3.439) | <.001∗ | – | |
| Drinking | 1.743 (1.304–2.331) | <.001∗ | – | |
| r-GT> 65 | 2.591 (1.458–4.604) | .001∗ | – | |
| Current Drinking + rGT> 65 | 3.754 (1.728–8.153) | .001∗ | – | |
| Morphologic type | ||||
| 1 | 1.064 (0.800–1.415) | .672 | – | |
| 2 | 9.750 (6.063–15.680) | <.001∗ | 6.261 (3.798–10.322) | <.001∗ |
| 3 | 2.304 (1.301–4.080) | <.05∗ | 1.867 (1.022–3.411) | .042∗ |
| 4 | 0.211 (0.025–1.759) | .150 | – | |
| 5 | 0.121 (0.080–0.184) | <.001∗ | 0.302 (0.188–0.485) | .008∗ |
| 6 | 2.566 (0.232–28.421) | .442 | – | |
| Exercise | ||||
| No | 1.0 (reference) | – | ||
| Yes | 1.033 (0.769–1.389) | .828 | ||
| Chronic disease | ||||
| Hypertension | 3.093 (1.881–5.087) | <.001∗ | 2.114 (1.220–3.663) | .008∗ |
| Diabetes mellitus | 3.157 (1.365–7.302) | <.001∗ | – | |
| Plasma markers | ||||
| Hs-CRP | 1.438 (0.928–2.227) | .104 | – | |
| Total cholesterol | 1.006 (1.002–1.010) | <.05∗ | – | |
| Triglyceride | 1.006 (1.004–1.008) | <.001∗ | – | |
Results were represented as estimated OR with the respective 95% CI. Variables with significant association in the univariate logistic regression analysis were included in multivariable logistic regression analysis with the forward conditional method.
BMI = body mass index, CI = confidence interval, GER-d = GER episodes noted, complicated with either mucosal erosions or strictures or both, over the distal esophagus, GER-s = GER episode observed, with smooth distal esophageal contour without mucosal erosions, strictures or scarring of the lower esophagus, Hs-CRP = high-sensitivity C- reactive protein, OR = odds ratio, r-GT = r-glutamyl transferase.
Indicates a significant association between the variable and GER-s and GER-d. (P < .05).