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. 2021 Sep 10;12:682724. doi: 10.3389/fimmu.2021.682724

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Copyright © 2021 Yang, Jiang, Peng and Li

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Differential metabolic profiles of tilapias cultured at different temperatures. (A) Heat map showing 97 differential metabolites. Red and blue indicate increase and decrease of metabolites relative to the median metabolite level, respectively (see color scale). (B) Z-score plot of differential metabolites based on the 18°C group. Each point represents one metabolite in one technical repeat and colored by sample types. (C) The different metabolites were classified into five categories, carbohydrate (23.71%), amino acid (29.9%), nucleotide (16.43%), fatty acid (18.56%), and others (11.34%). (D) Number of increased and decreased metabolites in these categories (C), 17 and 6 (carbohydrate), 24 and 5 (amino acid), 14 and 2 (nucleotide), 12 and 6 (fatty acid), and 8 and 3 (others), respectively.