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. 2021 Sep 20;11(5):585–589. doi: 10.1080/20009666.2021.1951943

Table 2.

Local and systemic side effects after first and second dose of both vaccines (Moderna and Pfizer)

Side Effect After the 1st dose After the 2nd dose
Local side effects    
Pain at the site of injection 185 (73.1%) 173 (68.4%)
Redness 8 (3.2%) 11 (4.3%)
Swelling 16 (6.3%) 16 (6.3%)
Itching 2 (0.8%) 1 (0.4%)
Systemic side effects    
None 95 (37.5%) 53 (20.9%)
Fatigue 63 (24.9%) 138 (54.5%)
Muscle soreness 111 (43.9%) 123 (48.6%)
Aches 44 (17%) 99 (39.1)
Joint Pain 18 (7.1%) 47 (18.6%)
Headache 48 (19%) 81 (32%)
Itching 1 (0.4%) 1 (0.4%)
Shortness of breath 0 0
Loss of consciousness 0 0
Fever 10 (4%) 54 (21.3%)
Skin rash 3 (1.1%) 2 (0.8%)
Nausea 10 (4%) 17 (6.7%)
Vomiting 0 0
Chills 2 (0.8%) 16 (6.3%)
Diarrhea 1 (0.4%) 3 (1.2%)
Metallic taste 2 (0.8%) 1 (0.4%)
Cough 2 (0.8%) 1 (0.4%)
Mental fogginess 1 (0.4%) 1 (0.4%)
Night sweats 1 (0.4%) 2 (0.8%)
Dizziness 0 1 (0.4%)
Insomnia 0 1 (0.4%)
Sweating 1 (0.4%) 1 (0.4%)
Runny nose 1 (0.4%) 0
Severe allergic reaction 1 (0.4%) 0
Malaise 0 1 (0.4%)
Swollen lymph node 1 (0.4%) 0