Table 4. Significance values (p) of the comparisons of systolic blood pressure and diastolic blood pressure obtained from home blood pressure monitoring according to the different combinations of two antihypertensive drugs, n= 6731.
| Combination of 2 drugs | ||||||||
|---|---|---|---|---|---|---|---|---|
| SBP comparisons | ACEI with CCB | ARB with DIUR | ACEI with DIUR | BB with ACEI | BB with ARB | BB with DIUR | BB with CCB | CCB with DIUR |
| ARB with CCB | 0.358 | 0.018 | 0.070 | 0.713 | 0.012 | <0.001 | 0.419 | 0.099 |
| ACEI with CCB | - | 0.317 | 0.239 | 0.332 | 0.004 | 0.001 | 0.696 | 0.023 |
| ARB with DIUR | - | - | 0.671 | 0.117 | <0.001 | 0.026 | 0.894 | 0.024 |
| ACEI with DIUR | - | - | - | 0.132 | 0.003 | 0.144 | 0.714 | 0.021 |
| BB with ACEI | - | - | - | - | 0.276 | 0.004 | 0.417 | 0.263 |
| BB with ARB | - | - | - | - | - | <0.001 | 0.093 | 0.641 |
| BB with DIUR | - | - | - | - | - | - | 0.129 | <0.001 |
| BB with CCB | - | - | - | - | - | - | - | 0.087 |
| DBP comparisons | ACEI with CCB | ARB with DIUR | ACEI with DIUR | BB with ACEI | BB with ARB | BB with DIUR | BB with CCB | CCB with DIUR |
|---|---|---|---|---|---|---|---|---|
| ARB with CCB | 0.133 | 0.195 | 0.800 | 0.995 | 0.842 | 0.270 | 0.204 | 0.077 |
| ACEI with CCB | - | 0.581 | 0.190 | 0.319 | 0.243 | 0.030 | 0.040 | 0.239 |
| ARB with DIUR | - | - | 0.317 | 0.485 | 0.366 | 0.065 | 0.072 | 0.166 |
| ACEI with DIUR | - | - | - | 0.856 | 0.725 | 0.475 | 0.343 | 0.087 |
| BB with ACEI | - | - | - | - | 0.903 | 0.397 | 0.313 | 0.145 |
| BB with ARB | - | - | - | - | - | 0.264 | 0.216 | 0.125 |
| BB with DIUR | - | - | - | - | - | - | 0.644 | 0.020 |
| BB with CCB | - | - | - | - | - | - | - | 0.043 |
Unpaired t test. ARB: angiotensin receptor blocker; ACEI: angiotensin-converting-enzyme inhibitor; CCB: calcium channel blocker; DIUR: diuretic; BB: beta-blocker; SBP: systolic blood pressure; DBP: diastolic blood pressure. Source: the authors.