Table II. Characterization of the mTS-mPAE-NPs.
Hydrodynamic diameter(nm) | Zeta potential(mV) | mPAE: siRNA ratio | Entrapment efficiency (%) | Loading capacity (%) | mTOR siRNA loading (μg/mg nanoparticles) |
---|---|---|---|---|---|
112.9 ± 8.2 | −2.8 ± 1.5 | 30:1 | 55.5 ± 2.8 | 1.83 ± 0.86 | 18.3 ± 8.6 |
114.2 ± 7.4 | +26.5 ± 5.3 | 45:1 | 99.9 ± 3.5 | 2.25 ± 0.34 | 22.2 ± 3.4 |
121.5 ± 6.5 | +32.2 ± 4.3 | 60:1 | 100 ± 4.2 | 1.66 ± 0.54 | 16.7 ± 5.4 |