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(A) In vitro pAkt assay comparing the bioactivity of native insulin and Ins-SA-Alb (native insulin EC50 = 2.126 nmol/L, Ins-SA-Alb EC50 = 30.32 nmol/L). (B) In vivo effects of Ins-SA-Alb and native insulin in STZ treated mice. Data were represented as mean ± SD, n = 4.
