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. 2020 Dec 13;11(9):2694–2708. doi: 10.1016/j.apsb.2020.12.005

Figure 2.

Figure 2

EPI-X4 WSC02 analogues inhibit X4-tropic HIV-1 infection with increased potency. WSC02 derivatives with either a single amino acid substitution (A), two distinct amino acid substitutions (B) or a combination of amino acid substitutions (C) were tested against X4-tropic HIV-1. TZM-bl reporter cells were preincubated with serially diluted peptide and afterwards inoculated with the virus. Infection rates were determined by β-galactosidase assay 3 days later. Data were represented as mean ± SEM (n = 3).