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. 2021 Mar 13;11(9):2859–2879. doi: 10.1016/j.apsb.2021.03.020

Figure 6.

Figure 6

FLZ treatment alleviates gut microbiota dysbiosis of the rotenone-induced PD mice. (A) Analysis of alpha diversity of gut microbiota by Shannon analysis. (B) Analysis of alpha diversity of gut microbiota by Simpson analysis. (C) PCoA plots of beta diversity based on weighted UniFrac Adonis analysis in different groups. (D) Beta diversity based on weighted UniFrac ANOSIM analysis in different groups. (E) Relative abundance of gut microbiota at the genus level in the three groups. (F) Heatmap analysis of relative abundance of gut microbiota at the genus level in different groups. (G)–(L) Relative abundance of six significantly altered bacterial genera: Akkermansia, Helicobacter, Alistipes, Enterorhabdus, Barnesiella, Olsenella. (M) Bar graph of LDA score of enriched KEGG pathways at level 3. LDA scores (log 10) > 2.7 and P < 0.05 are shown. In this figure, n = 7 for each group. Each boxplot represents the median, interquartile range, minimum and maximum values. #P < 0.05, ##P < 0.01, ###P < 0.001 versus the Control group; ∗P < 0.05, ∗∗P < 0.01 versus the Rotenone group.