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Effect of Bu8, MVIIA and MVIIC on CaV2.1 and CaV1.1. CaV2.1 currents were recorded using the same protocol as CaV2.2 (Fig. 4), CaV1.1 currents were recorded with a holding potential of −90 mV stepped to +20 mV. (A) CaV2.1, the concentration of peptide is 100 nmol/L and 10 μmol/L; (B) CaV1.1, the concentration of Bu8 and nifedipine is 10 μmol/L. n = 4–5. All data are presented as mean ± SEM.
