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. 2021 Sep 25;37(2):109823. doi: 10.1016/j.celrep.2021.109823

Figure 5.

Figure 5

S1-RBD-specific MBCs in SARS-CoV-2-infected individuals make a poor tertiary response

(A–E) Total log10 number of S1-RBD tetramer-binding total MBCs (A), plasmablasts (B), CD21+ cl-MBCs (C), CD21 CD27+ pb-MBCs (D), or CD21 CD21 CD11c+ at-MBCs (E) per million total B cells in the peripheral blood of SARS-CoV-2-naive (black circles) or SARS-CoV-2-infected (red circles) subjects (n = 5–12) at the indicated times after the second vaccination. Box and whisker plots are formatted as in Figure 1C. Values were compared with one-way ANOVA. p < 0.05, ∗∗∗∗p < 0.0001, ns, not significant.