Figure 2.

KEGG analyses indicate that DOX can induce dysregulation of MAPK signaling and hypertrophic pathways in cardiomyocytes

(A and B) KEGG pathways analysis of differentially expressed lncRNAs. The top 10 enrichment scores (−log₁₀[p value]) of the significant enrichment pathway of downregulated (A) and upregulated pathways (B) are shown. A p value denotes the enrichment p value of the pathway ID used the Fisher’s exact test. The enrichment score value of pathway ID is defined by (−log₁₀[p value]). The lower the p value, the higher the enrichment score, and the more significant is the pathway enrichment.