Table 2.
Immunogen | NCT Trial number | Other names | Phase | Adjuvant | Completion Date* |
---|---|---|---|---|---|
Prime: Ad4-Env CN54, MVA-CN54, Boost: CN54 gp140 | NCT03408262 | Ad4HIV | 1 | With protein boost: MPLA | Feb 2020 |
p24CE1/2 DNA, p55gag DNA | NCT03181789 | HVTN119 | 1 | IL-12 via DNA | Apr 2020 |
ChAdOx1.tHIVconsv1, MVA.tHIVconsv3, MVA.tHIVconsv4 | NCT04586673 | HIV-CORE0052 | 1 | Oct 2021 | |
Prime: Polyvalent DNA with subtype A/B/C/AE gp120 + Gag Boost: Tetravalent gp120 protein from subtypes A/B/C/AE |
NCT03409276 | HVTN124 | 1 | With protein boost: GLA-SE | Nov 2020 |
ChAdOx1.HTI and MVA.HTI | NCT04563377 | HIV-CORE0051 | 1/2a | Oct 2021 | |
ChAdOx1.tHIVconsv1, MVA.tHIVconsv3, MVA.tHIVconsv4 | NCT04553016 | HIV-CORE006 | 1 | Jun 2022 | |
Prime: Ad4-Env145NFL or Ad4-Env150KN Protein boost: 4571 gp140 trimer |
NCT03878121 | 19-I-0069 | 1 | With protein boost: Alum | Apr 2024 |
HCMV vectors expressing Gag, Rev/Tat/Nef, Pol, Env | NCT04725877 | VIR-1111–2001 | 1a | Dec 2024 |
Actual or predicted completion date