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. Author manuscript; available in PMC: 2022 Jul 14.
Published in final edited form as: Semin Immunol. 2021 Jul 14;51:101470. doi: 10.1016/j.smim.2021.101470

Table 2.

List of recent DNA and viral vectored vaccine clinical trials

Immunogen NCT Trial number Other names Phase Adjuvant Completion Date*
Prime: Ad4-Env CN54, MVA-CN54, Boost: CN54 gp140 NCT03408262 Ad4HIV 1 With protein boost: MPLA Feb 2020
p24CE1/2 DNA, p55gag DNA NCT03181789 HVTN119 1 IL-12 via DNA Apr 2020
ChAdOx1.tHIVconsv1, MVA.tHIVconsv3, MVA.tHIVconsv4 NCT04586673 HIV-CORE0052 1 Oct 2021
Prime: Polyvalent DNA with subtype A/B/C/AE gp120 + Gag
Boost: Tetravalent gp120 protein from subtypes A/B/C/AE
NCT03409276 HVTN124 1 With protein boost: GLA-SE Nov 2020
ChAdOx1.HTI and MVA.HTI NCT04563377 HIV-CORE0051 1/2a Oct 2021
ChAdOx1.tHIVconsv1, MVA.tHIVconsv3, MVA.tHIVconsv4 NCT04553016 HIV-CORE006 1 Jun 2022
Prime: Ad4-Env145NFL or Ad4-Env150KN
Protein boost: 4571 gp140 trimer
NCT03878121 19-I-0069 1 With protein boost: Alum Apr 2024
HCMV vectors expressing Gag, Rev/Tat/Nef, Pol, Env NCT04725877 VIR-1111–2001 1a Dec 2024
*

Actual or predicted completion date