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. Author manuscript; available in PMC: 2022 Oct 1.
Published in final edited form as: J Trauma Acute Care Surg. 2021 Oct 1;91(4):692–699. doi: 10.1097/TA.0000000000003350

Figure 3. Analysis of Bronchoalveolar Lavage (BAL) Leukocytes.

Figure 3.

(A) Cellular composition of leukocytes in bronchoalveolar lavage (BAL) after polytrauma + pneumonia (PT+PNA). Data represent the mean ± SD (n=3 in each group). **p < 0.01 (B) Microarray Transcriptomic Analysis of Bronchoalveolar Lavage Leukocytes. Heat map (log2) of the hierarchical clustering of BAL Leukocytes mRNA expression in (top) naïve old vs PT old vs PT+PNA old representing 979 Probe sets (829 Genes) at p<0.001 and (bottom) naïve young vs PT young vs PT+PNA young 262 Probe sets (95 Genes) at p<0.001. BAL leukocytes from old mice after PT+PNA had an increased number of changes in their transcriptome compared with young adult mice when compared with age matched controls. Data represent the mean ± SD (n=3 in each group). **p < 0.01Y, YNG = young; N = Naïve; O = old; P = treated; PT = polytrauma; PT+PAK = polytrauma + pneumonia

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