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. Author manuscript; available in PMC: 2022 Oct 1.
Published in final edited form as: J Trauma Acute Care Surg. 2021 Oct 1;91(4):692–699. doi: 10.1097/TA.0000000000003350

Figure 4. Proposed pathway for classic and pathologic myeloid activation in chronic critical illness after trauma.

Figure 4.

A blunted miR response (red circles) may be partly responsible for pathologic myeloid activation starting with HSPCs in the bone marrow of older adults. Modified from Kelly et al (37).