Table 3.

Baseline associations between biomarkers and physical performance measures

Variable		SPPB		6MWT		Grip (men)		Grip (women)
		r	p	r	p	r	p	r	p
Age (years)		− 0.28	< 0.001	− 0.33	< 0.001	− 0.30	< 0.001	− 0.28	0.008
Cystatin C (mg/l)		− 0.10	0.13	− 0.19	0.002	− 0.17	0.02	− 0.22	0.07
Creatinine (μmol/l)		0.02	0.72	0.04	0.51	− 0.06	0.41	− 0.08	0.45
Bicarbonate (mmol/l)		− 0.11	0.06	0.01	0.86	0.02	0.73	− 0.05	0.67
BMI(kg/m2)		0.12	0.05	− 0.18	0.002	0.05	0.46	0.07	0.51
eGFR (ml/min/1.73m2)		0.01	0.83	0.04	0.50	0.06	0.42	0.06	0.61
25OHD (nmol/l)		0.17	0.02	0.25	< 0.001	0.10	0.20	0.26	0.05
NT-pro-BNP (pg/ml)*		− 0.27	< 0.001	− 0.32	< 0.001	− 0.31	< 0.001	− 0.12	0.35
Albumin (g/l)		0.14	0.02	0.20	< 0.001	0.12	0.10	0.10	0.35
Haemoglobin (g/dl)		0.15	0.014	0.22	< 0.001	0.12	0.08	0.10	0.38
Phosphate (mmol/l)		− 0.07	0.28	− 0.01	0.89	− 0.07	0.35	0.02	0.86
		Mean (SD)	p	Mean (m) (SD)	p
Sex	Men	8.3 (2.2)	0.01	328 (129)	0.001	N/A	N/A	N/A	N/A
	Women	7.5 (2.4)		270 (137)		N/A	N/A	N/A	N/A

All Pearson’s correlations except for *Spearman’s rho

SPPB Short Physical Performance Battery, 6WMD Six-minute walk distance, BMI body mass index, eGFR estimated glomerular filtration rate, 25OHD 25-hydroxyvitamin D, NT-pro-BNP N-terminal pro B-type natriuretic peptide