Table 2.

ROC analysis for the detection of LVO patients

(N = 145)	AUC (95% CI)		P Value	Y‑Index	Y Index CP	Spec ≥70% CP
Overall LVO Population (n = 79) vs. Controls (n = 66)
CTA Hemispheric AR	0.96	(0.91–0.98)	<0.001	0.84	0.926	0.955
CTA Min/Max AR Ratio	0.97	(0.92–0.99)	<0.001	0.88	0.810	0.889
CTA M2 Territory AR	0.95	(0.90–0.98)	<0.001	0.84	0.922	0.941
ICA and M1 Occlusion (n = 72) vs. Controls (n = 66)
CTA Hemispheric AR	0.98	(0.94–1.00)	<0.001	0.89	0.926	0.955
CTA Min/Max AR Ratio	0.98	(0.94–1.00)	<0.001	0.92	0.810	0.955
CTA M2 Territory AR	0.95	(0.91–0.98)	<0.001	0.87	0.922	0.955
M2 Occlusion (n = 7) vs. Controls (n = 66)
CTA Hemispheric AR	0.72	(0.60–0.82)	0.14	0.51	0.935	0.955
CTA Min/Max AR Ratio	0.81	(0.70–0.90)	0.005	0.57	0.785	0.889
CTA M2 Territory AR	0.85	(0.74–0.92)	<0.001	0.55	0.941	0.941
CTA ASPECTS M5 Region AR	0.92	(0.84–0.97)	<0.001	0.78	0.919	0.919

Cut points were determined by the Y‑Index and sensitivity threshold of ≥0.70

ROC indicates, receiver operating characteristics, LVO large vessel occlusion, AUC area under the curve, CI confidence interval, Y‑Index Youden Index, Spec specificity, CP cut point, CTA CT angiography, AR asymmetry ratio, ICA internal carotid artery, M1 M1 segment of the middle cerebral artery, M2 M2 segment of the middle cerebral artery, ASPECTS Alberta Stroke Program Early CT Score

P values <0.05 indicate statistical significance