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. 2021 Jan 25;42(10):1610–1619. doi: 10.1038/s41401-020-00597-x

Fig. 4. Impact of TLR4 knockout (TLR4−/−) on LPS-induced hepatocyte apoptosis.

Fig. 4

Apoptosis in hepatic tissues was determined by TUNEL assays, caspase 3 activity assays, and Western blotting, and the results show the expression of apoptosis-associated proteins. a Representative TUNEL staining images for each group (original magnification, ×400). b The number of TUNEL-positive cells in each group. c Caspase 3 activity. d Bcl-2 expression. e Bax expression. Mean ± SEM, n = 6–8 mice in each group; *P < 0.05 between the indicated groups.