Table 1.

Baseline characteristics in all patients infected with SFTSV.

Variables	Recovered patients (n = 30)	Deceased patients (n = 11)	P value
Age, years	63.6 (56.2–71.1)	65.4 (62.7–71.3)	0.494
Males, %	18 (58.1%)	6 (60.0%)	0.914
Duration, daysa	19.0 (16.0–24.3)	10.0 (8.0–11.0)	1.80 × 10−5
SFTSV, IU/mLb	1.66 × 104 (5.60 × 102−2.28 × 105)	3.67 × 106 (4.01 × 105−3.83 × 107)	4.961 × 10−4
Complete blood count
WBC, ×109/ L	3.46 (1.90–4.35)	2.75 (1.68–7.17)	0.976
Neutrophil, ×109/L	1.87 (1.20–3.81)	1.15 (0.73–5.15)	0.564
Lymphocyte, ×109/L	0.60 (0.46–1.04)	0.76 (0.50–1.67)	0.387
RBC, ×1012/L	4.12 (3.88–4.47)	3.61 (3.42–4.26)	0.029
Hemoglobin, g/L	129.0 (118.6–140.0)	120.0 (104.8–141.0)	0.274
Platelet, ×109/L	43.0 (22.0–55.0)	35.0 (14.0–45.8)	0.261
CRP, mg/L	3.60 (2.19–18.30)	8.96 (6.07–11.84)	0.351
Coagulation
PT, s	11.60 (10.60–12.20)	12.10 (11.63–12.70)	0.164
APTT, s	37.20 (33.00–44.40)	63.50 (47.40–66.75)	2.368 × 10−4
Liver function
ALT, U/L	88.0 (47.0–147.0)	142.00 (108.5–191.5)	0.033
AST, U/L	221.0 (108.0–486.0)	825.00 (459.0–1299.5)	1.132 × 10−3
TBIL, μmol/L	10.20 (7.80–13.40)	10.30 (9.40–22.80)	0.315
Renal function
BUN, mmol/L	5.04 (3.70–6.72)	7.95 (4.83–12.55)	0.022
Creatinine, μmol/L	68.0 (62.60–84.40)	90.00 (70.50–145.80)	0.041

Data are median (IQR) or n (%). P values were calculated by two-sided Mann–Whitney U test or χ² test.

WBC white blood cell, RBC red blood cell, CRP C-reactive protein, PT prothrombin time, APTT activated partial thromboplastin time, ALT alanine aminotransferase, AST aspartate aminotransferase, TBIL total bilirubin, BUN blood urea nitrogen.

^aDuration was defined as days from onset to outcomes.

^bIU indicates 50% tissue culture infective dose (TCID50), 10x TCID50/mL = 0.496 × 10^x+3 copies/mL. Statistic analysis was performed with log10-transformation of SFTSV viral load.