Table 3.
The MRS-derived absolute concentrations of metabolites (mean ± SEM), which significantly changes after stress. GABA, Glu, Gln, Glx, tCr, and total NAA (tNAA = NAA + NAAG) decreased, while mIns increased under stress. *p < 0.05.
| Metabolite | Concentration at baseline (mM) | Concentration after stress (mM) | p-value |
|---|---|---|---|
| GABA | 2.4 ± 0.2 | 1.9 ± 0.2* | 0.03 |
| Glu | 11.0 ± 0.6 | 8.4 ± 0.2* | 0.039 |
| Gln | 5.5 ± 0.4 | 4.3 ± 0.2* | 0.049 |
| mIns | 6.9 ± 0.3 | 7.3 ± 0.2* | 0.049 |
| Glx = Glu + Gln | 18.9 ± 1.1 | 14.6 ± 0.4* | 0.042 |
| tCr = Cr + PCr | 10.0 ± 0.6 | 7.9 ± 0.4* | 0.034 |
| tNAA = NAA + NAAG | 9.1 ± 0.4 | 7.4 ± 0.6* | 0.048 |