Skip to main content
. 2021 Jan 13;42(10):1653–1664. doi: 10.1038/s41401-020-00578-0

Table 2.

Summary of cytotoxicity and suppressive activities.

Compounds CC50 Con A IC50 SI LPS IC50 SI
(μM) (μM) (μM)
SOMCL-17-016 9.44 ± 0.25 0.59 ± 0.17 17.44 ± 4.5 0.02 ± 0.01 601.88 ± 202.29
Ibrutinib 1.91 ± 0.16 0.46 ± 0.22 5.19 ± 2.16 0.07 ± 0.02 28.20 ± 5.45
Acalabrutinib 30.87 ± 2.17 13.87 ± 3.42 2.41 ± 0.75 0.66 ± 0.11 47.81 ± 4.56

CC50, The cytotoxic concentration of the compound that reduces cell viability by 50%; IC50, The inhibitory concentration of the compound that reduces cell proliferation by 50%; Selective Index (SI) = CC50/IC50.