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. 2021 Sep 24;12:5645. doi: 10.1038/s41467-021-26023-2

Table 2.

AI performance on the internal test set across different sub-populations. We reported the AUROC of the AI system with 95% confidence intervals on the internal test set. The biopsied population only includes exams where at least one biopsy was recommended. We stratified exams based on patient age, mammographic breast density, and the manufacturer of the US devices. Mammographic breast density was categorized based on the BI-RADS standards69.

Population AUROC (95% CI) No. of breasts No. of cancers
Overall population 0.976 (0.972, 0.980) 79,078 1248
Biopsied population 0.940 (0.934, 0.947) 12,973 1248
Age
 < 40 yrs old 0.969 (0.955, 0.982) 5176 72
 40 − 49 yrs old 0.970 (0.955, 0.986) 19,677 160
 50 − 59 yrs old 0.981 (0.975, 0.986) 24,142 292
 60 − 69 yrs old 0.980 (0.973, 0.985) 19,039 326
 ≥70 yrs old 0.969 (0.958, 0.981) 11,044 398
Breast density
 Entirely fatty 0.964 (0.942, 0.983) 1157 54
 Scattered fibroglandular densities 0.975 (0.961, 0.982) 19,199 441
 Heterogeneously dense 0.979 (0.974, 0.981) 47,255 610
 Extremely dense 0.964 (0.932, 0.973) 9398 90
 Unkown 0.970 (0.955, 0.983) 2069 53
Manufacturer
 GE 0.984 (0.968, 0.993) 5708 47
 Medison 0.990 (0.974, 0.996) 2673 13
 Philips 0.977 (0.970, 0.982) 28,943 412
 Siemens 0.974 (0.968, 0.980) 37,572 699
 Toshiba 0.986 (0.978, 0.992) 4180 77
Other 2 0