Comparison of event-based analysis Kaplan-Meier curves of two-dimensional retinal nerve fiber layer (RNFL) thickness measurement across global overall, inferior, and superior quadrants methods. Log-rank tests were used to compare the global RNFL thickness method to the inferior quadrant and superior quadrant methods, with P = 0.09 and P = 0.74 respectively. Additionally, for the comparison between the inferior quadrant and superior quadrant, P = 0.06, indicating that there is no significant difference among the three methods in detecting glaucoma progression using event-based criterion. The Holm method was used to adjust the log-rank tests for multiple comparisons.