Table 2.

Type I error rates of the different approaches for the large Worldwide sample.

	CAST	PC3	LMM	LocPerm
A—No stratification
RVs	0.00085	0.00099	0.00093	0.00087
LFVs		0.00099	0.00094
CVs		0.00099	0.00093
ALLVs		0.00099	0.00093
B—Moderate stratification
RVs	0.00681	0.00259	0.00456	0.00096
LFVs		0.00109	0.00123
CVs		0.00105	0.00117
ALLVs		0.00128	0.00162
C—High stratification
RVs	0.13698	0.00662	0.01834	0.00113
LFVs		0.0012	0.00163
CVs		0.00119	0.00115
ALLVs		0.00127	0.00266

The nominal level alpha considered is $\alpha =0.001$ and the corresponding 95%PI adjusted for the 10 methods is [0.00079–0.00121]. Type I error rates under the lower bound of the 95%PI are displayed in italic and above the upper bound of the 95%PI in bold.