Table.
SENECA Trial Findings of 3 Patients
| Relative Change From Baseline at 12 Months |
Average Absolute Change From Baseline at 12 Months |
|||
|---|---|---|---|---|
| MSC Treated (n = 1) | Placebo Treated (n = 2) | MSC Treated (n = 1) | Placebo Treated (n = 2) | |
| Left ventricular ejection fraction | +19 | +18a | +7 | +7a |
| Global longitudinal strain | −15 | +18 | −1.84 | +1.99 |
| Left ventricular myocardial scar | −20 | +64a | −2.70 | +3.86a |
| 6-min walk test | +18 | +6 | +68.5 feet | +18 feet |
| Minnesota living with heart failure questionnaire | −51 | −7 | −24.85 points | −5 points |
Values are % unless otherwise indicated. The table reflects the relative percentage change from baseline achieved by 3 trial patients at 12 months of follow-up.
MSC = mesenchymal stem cell.
a
Incomplete 12-month data, n = 1.