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Comparison of overall structure (top), cofactor solvent exposure (middle), and location of solvent channels for superoxide access (bottom) in class Ib (A) (PDB accession code3N3A), class Id (B) (PDB accession code6CWQ), and class Ie RNR (C) (PDB accession code6EBO). Selected amino acids shown in stick format and MnII ions shown as purple spheres. Coordination interactions or hydrogen bonds shown as dashed lines. Water molecules shown as red spheres.
