Table 1.

Variability indicator of Type 2 inflammatory biomarkers

Blood eos	Formula
Blood eos geometric CV	SD of blood eos geometric mean/Blood eos geometric mean
ΔBlood eos	Blood eos (max-min)
%Blood eos	Δ Blood eos/multiple measurements mean
Blood eos (min/max %)	Blood eos (min/max)
FeNO	Formula
FeNO geometric CV	SD of FeNO geometric mean/FeNO geometric mean
ΔFeNO	FeNO (max-min)
%FeNO	ΔFeNO/multiple measurements mean
FeNO (min/max %)	FeNO (min/max)
Sputum eos	Formula
Sputum eos CV	SD of Sputum eos mean/Sputum eos mean
ΔSputum eos	Sputum eos (max-min)
%Sputum eos	ΔSputum eos/multiple measurements mean
Sputum eos (min/max %)	Sputum eos (min/max)
IgE	Formula
IgE geometric CV	SD of IgE geometric mean/IgE geometric mean
ΔIgE	IgE (max-min)
%IgE	ΔIgE/multiple measurements mean
IgE (min/max %)	IgE (min/max)

CV, coefficient of variation. eos, eosinophils. Δ Blood eos, change in blood eos. FeNO, fraction of exhaled nitric oxide. Δ FeNO, change in FeNO. IgE, total immunoglobulin E. Δ IgE, change in IgE. max, maximum over measurements. min, minimum over measurements. min/max %: minimum as a percentage of maximum. SD, standard deviation. Sputum eos, percentage of sputum eosinophils. Δ Sputum eos, change in sputum eos