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. 2021 Mar 17;33:253–264. doi: 10.1016/j.jare.2021.03.005

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© 2021 The Authors. Published by Elsevier B.V. on behalf of Cairo University. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 1 — TMEM16A promoted the migration and invasion of MCF-7 cells. A. TMEM16A protein expression in MCF-7 cells treated with scrambled shRNA and TMEM16A-shRNA (T16A-shRNA) or empty vector and TMEM16A-containing plasmids (T16A-OE). B. The wound healing assay showed the migration of MCF-7 cells treated with scrambled shRNA and T16A-shRNA or empty vectors and T16A-OE plasmids. C. Quantification of the results of the wound healing assay shown in B. n = 3. *p < 0.05 vs scrambled; #p < 0.05 vs vector. D. Transwell assays indicating migration (top) and invasion (bottom) of MCF-7 cells treated with scrambled shRNA and T16A-shRNA, or empty vector and T16A-OE plasmids. E, F. Quantification results for cell migration (E) and invasion (F) shown in D. n = 3. *p < 0.05 vs scrambled; #p < 0.05 vs vector.