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. 2021 Jul 8;17(2):401–408. doi: 10.4103/1673-5374.317987

Figure 6.

Figure 6

Nde1 overexpression promotes activation of the Wnt/β-catenin pathway.

(A) Wnt3a, β-catenin, GSK-3β, p-GSK-3β, LEF1, c-myc, c-Jun, and cyclin D1 protein expression are induced by Ndel1 overexpression. (B) Quantification of Wnt3a, β-catenin, GSK-3β, p-GSK-3β, LEF1, c-myc, c-Jun, and cyclin D1 protein expression results. The data are presented as mean ± SD from three independent experiments. *P< 0.05, **P< 0.01, ***P< 0.001 (one-way analysis of variance followed by Tukey's post hoc test). c-myc: MYC proto-oncogene; GSK-3β: glycogen synthase kinase 3β; LEF1: lymphoid enhancer binding factor 1; Ndel1: NudE neurodevelopment protein 1-like 1; p-GSK-3β: phospho-glycogen synthase kinase 3β.