Table 5.
Subgroup analyses for value of modified Rapid Acute Physiology Score (mREMS) in prediction of in-hospital mortality
| Parameter | No. analyses | AUC | Sensitivity | Specificity | PLR | NLR | DOR |
|---|---|---|---|---|---|---|---|
| mREMS score | |||||||
| 3 to 9 | 8 | 0.73 [0.69 - 0.77] | 0.89 [0.77, 0.95] | 0.25 [0.10, 0.50] | 1.2 [1.0, 1.5] | 0.44 [0.27, 0.72] | 3 [1, 5] |
| 10 to 14 | 5 | 0.62 [0.58 - 0.66] | 0.30 [0.17, 0.47] | 0.79 [0.68, 0.87] | 1.5 [1.2, 1.8] | 0.88 [0.78, 1.00] | 2 [1, 2] |
| Study type | |||||||
| Cohort | 13 | 0.64 [0.60 - 0.68] | 0.74 [0.50, 0.89] | 0.46 [0.25, 0.6 | 1.4 [1.1, 1.7] | 0.56 [0.38, 0.82] | 2 [2, 4] |
| Case-control | 0 | --- | --- | --- | --- | --- | --- |
| Cross sectional | 0 | --- | --- | --- | --- | --- | --- |
| Study design | |||||||
| Prospective | 12 | 0.65 [0.61 - 0.69] | 0.75 [0.47, 0.91] | 0.48 [0.25, 0.72] | 1.4 [1.1, 1.9] | 0.52 [0.33, 0.82] | 3 [2, 4] |
| Retrospective | 1 | NA | NA | NA | NA | NA | NA |
| Setting of patients | |||||||
| Trauma | 1 | NA | NA | NA | NA | NA | NA |
| Sepsis/infection | 11 | 0.59 [0.55 - 0.63] | 0.73 [0.47, 0.89] | 0.41 [0.21, 0.65] | 1.2 [1.1, 1.4] | 0.65 [0.48, 0.88] | 2 [1, 3] |
| Non-trauma settings | 0 | NA | NA | NA | NA | NA | NA |
| All acute settings | 1 | NA | NA | NA | NA | NA | NA |
Data are presented as value [95% confidence interval].
AUC: Area under the curve; DOR: Diagnostic odds ratio; NA: Not applicable since there is a small number of studies; NLR: Negative likelihood ratio; PLR: Positive likelihood ratio.