TABLE.
COVID-19–Associated Acute Large Vessel Occlusive Stroke in Children and Adolescents
| Case | Age, Sex | Vessel Distribution | COVID | MIS-C Criteria met? | Organ Involvement | Treatment |
|---|---|---|---|---|---|---|
| CASE 1 | 15, F | L. MCA | + PCR 1 wk prior + serology |
Yes | Cardiac, renal | IVIG, methylprednisolone, prednisone, enoxaparin |
| CASE 2 | 16, F | L. ICA terminus | + serology only | Yes | Cardiac, renal, GI | IVIG, methylprednisolone, prednisone, enoxaparin, aspirin |
| Tiwari10 | 9, F | R. MCA | + PCR At presentation |
Yes | Cardiac | IVIG, methylprednisolone, dexamethasone, remdesivir, LMWH |
| Beslow (1)8 | 10, M | R. MCA + cerebellar infarcts | + PCR 1 wk prior + serology |
Yes | Not specified | Not specified |
| Beslow (2)8 | 14, M | R. MCA + R. ACA |
+ PCR 1 wk post stroke |
Yes | Respiratory, GI | Not specified |
| Beslow (3)8 | 10, M | B. PCA | + PCR 1 wk post stroke |
No | Respiratory | Not specified |
| Beslow (4)8 | 16, M | L. MCA + B. ACA |
+ PCR 1 wk prior |
No | Not specified | Not specified |
| Appavu (1)11 | 8, F | B. MCA | + PCR 3 weeks prior + serology |
No | None | Thrombectomy |
| Appavu (2)11 | 16, M | L. MCA | + PCR 4 weeks prior |
No | Cardiac, renal | Enoxaparin only |
| Gulko12 | 13, F | L. MCA | + PCR At presentation |
No | None | Not specified |
| Mirzaee13 | 12, M | L. MCA | + PCR At presentation |
No | None | “conservative” |
Abbreviations:
ACA = anterior cerebral artery
B = bilateral
ICA = internal carotid artery
IVIG = intravenous immunoglobulin
L = Left
LMWH = low molecular weight heparin
MCA = middle cerebral artery
PCA = posterior cerebral artery
PCR = polymerase chain reaction
R = right