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. 2021 Aug 20;49(17):10120–10135. doi: 10.1093/nar/gkab711

Graphical Abstract.

Graphical Abstract

The iron sensor IdeR recognizes its DNA targets, consisting of a 19-bp palindrome binding two IdeR dimers or a 10-bp palindrome binding one dimer, by their sequence-dependent shape rather than through specific contacts with the DNA bases.