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. 2021 Sep 24;21:302. doi: 10.1186/s12890-021-01674-5

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — Distribution and variation trend of PIFR in COPD/Asthma group, ND/FU group, AE/Stable group and all patients. Figure describes the distribution and changes of PIFR_BT and PIFR_AT for patients using DPIs in COPD/Asthma group, ND/FU group, AE/Stable group and all patients. a is a box diagram showing the improvement from PIFR_BT to PIFR_AT in COPD/Asthma group. b is a box diagram showing the improvement from PIFR_BT to PIFR_AT in ND/FU group. c is a box diagram showing the improvement from PIFR_BT to PIFR_AT in AE/Stable group. d is a line chart for PIFR_BT and PIFR_AT in all patients, which the two values corresponding to each abscissa value are PIFR_BT and PIFR_AT of the same patient. When the patient's PIFR was relatively low, training increases the PIFR value more obviously. COPD, chronic obstructive pulmonary disease; AE, acute exacerbation; ND, newly-diagnosed; FU, follow-up; PIFR_BT, peak inhalation flow rate measured before-training; PIFR_AT, peak inhalation flow rate measured after training