Table 2.
Short and long-term outcomes of MIOCA and MINOCA ACS patients, according to admission hyperglycemia
| MIOCA N = 2198 |
MINOCA N = 233 |
HGL MIOCA vs MINOCA | |||||
|---|---|---|---|---|---|---|---|
| no-aHGL N = 1321 |
aHGL N = 877 |
p-value | no-aHGL N = 195 |
aHGL N = 38 |
p-value | p-value | |
| Short-term outcomes | |||||||
| In-hospital death, n (%) | 10 (0.8) | 40 (4.6) | < 0.001 | 1 (0.5) | 1 (2.6) | ns | ns |
| With T2DM | 0 (0) | 20 (4.4) | 0.020 | – | – | – | |
| Intra-hospital arrhythmias, n (%) | 59 (4.5) | 84 (9.7) | < 0.001 | 5 (2.6) | 5 (13.5) | 0.003 | ns |
| Atrial fibrillation, n (%) | 39 (3) | 52 (6) | 2 (1) | 3 (7.9) | |||
| Ventricular arrhythmias, n (%) | 20 (1.5) | 32 (3.6) | 3 (1.5) | 2 (5.7) | |||
| IABP, n (%) | 12 (0.9) | 34 (3.9) | < 0.001 | – | – | – | |
| Hospital length of stay days, median [IQR] | 5 [4–7] | 6 [4–10] | < 0.001 | 5 [4–6] | 5 [4–8] | ns | ns |
| Long-term outcomes* | |||||||
| All-cause death, n (%) | 117 (8.9) | 143 (17.2) | < 0.001 | 15 (7.7) | 8 (22.9) | 0.006 | ns |
| With T2DM | 20 (16.9) | 80 (18.4) | 0.718 | 2 (15.4) | 4 (26.7) | 0.468 | |
| Cardiovascular-death, n (%) | 67 (5.1) | 84 (10.1) | < 0.001 | 7 (3.6) | 5 (14.3) | 0.009 | ns |
| With T2DM | 11 (9.3) | 51 (11.7) | 0.46 | 1 (7.7) | 3 (20.0) | 0.35 | |
| Re-AMI, n (%) | 58 (4.4) | 41 (4.7) | ns | 1 (0.5) | 0 (0) | ns | ns |
| Stroke, n (%) | 2 (0.2) | 1 (0.1) | ns | 0 (0) | 0 (0) | ns | ns |
| Heart failure, n (%) | 108 (10.3) | 103 (15.8) | 0.001 | 8 (5.2) | 4 (15.4) | ns | ns |
| MACE, n (%) | 212 (16) | 251 (28.6) | < 0.001 | 20 (10.3) | 7 (18.4) | ns | ns |
| MAE, n (%) | 260 (19.7) | 304 (34.7) | < 0.001 | 27 (13.8) | 10 (26.3) | ns | ns |
Continuous variables are presented as median (IQR) while categorical ones as n (%)
no-aHGL admission normal glucose level, aHGL admission high glucose level, T2DM type 2 diabetes mellitus, IABP Intra-Aortic Balloon Pump, AMI acute myocardial infarction, MACE major adverse cardiovascular event, MAE major adverse event
Long term outcomes (*): MIOCA no-aHGL (N = 1308); MIOCA aHGL (N = 833); MINOCA no-aHGL (N = 194); MINOCA aHGL (N = 35)