Table 3.
Patient | Status | Age at Dx (years) | Blast% | G-banding Karyotype | Molecular diagnostic (28 translocations) | AML prognostic marker |
---|---|---|---|---|---|---|
1 | P | 26 | 55 | 46,XX [20] | Negative |
NPM1 (MutA) positive, FLT3-ITD positive |
R | 30 | 46,XX [20] | Negative |
NPM1 (MutA) positive, FLT3-ITD negative |
||
2 | P | 17 | > 80 | 46,XX [20] | Negative | NPM1 negative, FLT3-ITD negative |
R | 60 | 46,XX [20] | Negative | NPM1 negative, FLT3-ITD negative | ||
3 | P | 43 | 91 | 46,XY [20] | Negative | NPM1 negative, FLT3-ITD negative |
R | 94 | 46,XY [20] | Negative | NPM1 negative, FLT3-ITD negative | ||
4 | P | 40 | 11 | 46,XY [20] | Negative | NPM1 negative, FLT3-ITD negative |
R | 70 | 46,XY [20] | Negative | NPM1 negative, FLT3-ITD negative | ||
5 | P | 51 | 54 | 46,XY [20] | Negative |
NPM1 (MutA) positive, FLT3-ITD negative |
R | 20 | 46,XY [20] | Negative |
NPM1 (MutA) positive, FLT3-ITD negative |
||
6 | P | 33 | 61 | 46,XX [20] | Negative | NPM1 negative, FLT3-ITD negative |
R | 91 | 46,XX [20] | Negative | NPM1 negative, FLT3-ITD negative |