Table 2.
Genotype frequency of MTHFR C677T gene polymorphisms in MCI patients and the control group.
| Author (year) | Genotype | HWE | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCI patients | Control | ||||||||||
| C | T | CC | CT | TT | C | T | CC | CT | TT | ||
| Roussotte (2017) [36] | 455 | 263 | 149 | 157 | 53 | 264 | 148 | 84 | 96 | 26 | p > 0.05 |
| Luo (2015) [37] | 175 | 83 | 62 | 51 | 16 | 190 | 72 | 67 | 56 | 8 | p > 0.05 |
| Kaur (2018) [38] | 451 | 75 | 194 | 63 | 6 | 444 | 108 | 179 | 86 | 11 | p > 0.05 |
| El-Batch (2010) [39] | 36 | 20 | 11 | 14 | 3 | 33 | 7 | 14 | 5 | 1 | p > 0.05 |
| Zou (2016) [40] | 181 | 67 | 61 | 59 | 4 | 173 | 75 | 62 | 49 | 13 | p > 0.05 |
| Xing (2019) [41] | 46 | 54 | 15 | 16 | 19 | 83 | 37 | 32 | 19 | 9 | p < 0.05 |
| Wang (2019) [42] | 216 | 114 | 82 | 52 | 31 | 165 | 59 | 68 | 29 | 15 | p < 0.05 |
| Li (2017) [43] | 54 | 76 | 17 | 20 | 28 | 77 | 49 | 28 | 21 | 14 | p < 0.05 |
MCI: mild cognitive impairment; HWE: Hardy–Weinberg Equilibrium; OR: odds ratio.