Table 3.

Meta-analysis of the association between MTHFR C677T polymorphisms and MCI susceptibility and Egger's test.

Comparison	N	Model	Pooled estimate value				Heterogeneity		p for Egger's test
			OR	95% CI	Z	p	I 2	p
T vs. C	8	Random	1.318	0.964-1.801	1.73	0.084	78.6%	≤0.001	0.066
CT+TT vs. CC	8	Random	1.296	0.925-1.817	1.51	0.132	68.4%	0.002	0.006
TT vs. CC+CT	8	Random	1.397	0.845-2.312	1.30	0.193	62.1%	0.010	0.859
CT vs. CC	8	Fixed	1.031	0.855-1.243	0.32	0.749	46.3%	0.071	0.005
TT vs. CC	8	Random	1.506	0.850-2.667	1.40	0.160	67.1%	0.003	0.859

N: number of cases; OR: odds ratio; 95% CI: 95% confidence intervals; Z: Z test; p: p value; I²: I² test.