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. 2021 Sep 17;2021:7394344. doi: 10.1155/2021/7394344

Figure 5.

Figure 5

Effect of c-Src inhibiton on EMT and tubulointerstitial fibrosis in renal tubule of diabetic mice. (a) HE and Masson's trichrome staining of kidney sections (original magnification ×400). (b) Immunohistochemical staining of kidney sections with E-cadherin and α-SMA (original magnification ×400). (c) The expression levels of E-cadherin and α-SMA analyzed by western blotting. (d) The expression levels of PPARγ and UCP2 analyzed by western blotting. (e) The expression levels of DRP1 and FIS1 analyzed by western blotting. The number of mice in every group was 10. 10 visual fields were randomly selected from each group, and the area percent of staining was calculated for statistical analysis. All western blotting experiments were performed independently at least in triplicate. Values are expressed as means ± SD. ∗p < 0.05 versus db/m group. ∗∗p < 0.01 versus db/m group. #p < 0.05 versus db/db group. ##p < 0.01 versus db/db group.