Table 2.
The detailed information on the KEGG enrichment analysis of DEGs in GSE33744.
| Term | Pathway | Count | p value | Genes |
|---|---|---|---|---|
| mmu05200 | Pathways in cancer | 27 | 0.003017125 | ITGB1, CDKN1A, LAMA1, LPAR1, ADCY1, LPAR4, RASGRP2, PTGS2, EGFR, GLI3, ADCY5, FGF6, GNG2, BID, RUNX1T1, FZD3, FZD2, PTCH1, MMP2, PTCH2, VEGFB, BMP2, TRAF4, CCNE1, COL4A6, GNB4, CYCS |
| mmu04151 | PI3K-Akt signaling pathway | 23 | 0.010735996 | ITGB1, CDKN1A, ANGPT2, ANGPT1, LAMA1, NOS3, FLT4, TNC, VEGFB, LPAR1, IL4RA, LPAR4, EPOR, EGFR, FGF6, NR4A1, GNG2, CCNE1, GNB4, COL4A6, ITGB6, TLR4, ITGA9 |
| mmu04080 | Neuroactive ligand-receptor interaction | 20 | 0.009368143 | GABRB3, GABRB1, CHRNA4, GRID1, CHRNA7, P2RY14, GABRA4, C5AR1, LPAR1, LPAR4, NR3C1, ADRA1A, P2RX7, GLRA2, CALCR, CNR1, HRH2, P2RX1, ADORA3, TSHB |
| mmu04010 | MAPK signaling pathway | 17 | 0.024073268 | NTRK2, MEF2C, GADD45B, PLA2G4B, CACNA2D4, RASGRP2, EGFR, CACNA1G, FGF6, NR4A1, CACNG7, CACNB3, MAP3K8, MAP3K6, HSPA1B, MAP4K4, HSPA1A |
| mmu04015 | Rap1 signaling pathway | 15 | 0.027634917 | ITGB1, ANGPT2, ANGPT1, FLT4, VEGFB, LPAR1, ADCY1, LPAR4, RASGRP2, EGFR, ADCY5, FGF6, CNR1, PRKD3, RAPGEF5 |
| mmu04014 | Ras signaling pathway | 15 | 0.044994767 | PLA2G12B, ANGPT2, PLA2G2E, ANGPT1, PLA2G4B, FLT4, VEGFB, GAB2, RASGRP2, EGFR, FGF6, GNG2, GNB4, RIN1, RAPGEF5 |
| mmu04921 | Oxytocin signaling pathway | 13 | 0.009629191 | RYR1, MEF2C, CDKN1A, NOS3, PLA2G4B, NFATC2, CACNA2D4, ADCY1, COX-2, EGFR, ADCY5, CACNG7, CACNB3 |
| mmu00230 | Purine metabolism | 13 | 0.033776013 | ENTPD1, ENTPD2, PDE6H, GDA, PDE1A, AK1, NME4, NME5, ADCY1, ADCY5, ADSSL1, ENPP3, PDE8B |
| mmu04020 | Calcium signaling pathway | 13 | 0.03503903 | RYR1, NOS3, PDE1A, CHRNA7, ADCY1, ADRA1A, EGFR, CACNA1G, P2RX7, SLC8A3, GNA14, HRH2, P2RX1 |
| mmu00590 | Arachidonic acid metabolism | 12 | 0.000415 | PTGIS, PLA2G2E, PLA2G12B, CYP2J13, PLA2G4B, GPX7, ALOX12B, CYP4A14, LTC4S, COX-2, PTGDS, PTGS1 |
| mmu05414 | Dilated cardiomyopathy | 11 | 0.000926 | ITGB1, CACNG7, CACNB3, TNNT2, TPM1, DAG1, CACNA2D4, ITGB6, ADCY1, ADCY5, ITGA9 |
| mmu04726 | Serotonergic synapse | 11 | 0.024426847 | GABRB3, GABRB1, GNG2, CYP2J13, KCND2, PLA2G4B, GNB4, ALOX12B, COX-2, ADCY5, PTGS1 |
| mmu04976 | Bile secretion | 9 | 0.004518526 | ABCC3, SLCO1A1, SLCO1A5, ADCY1, SLC51A, ABCB1A, SLC22A7, ABCB1B, ADCY5 |
| mmu05410 | Hypertrophic cardiomyopathy | 9 | 0.008596921 | ITGB1, CACNG7, CACNB3, TNNT2, TPM1, DAG1, CACNA2D4, ITGB6, ITGA9 |
| mmu04512 | ECM-receptor interaction | 9 | 0.015941382 | ITGB1, SV2B, LAMA1, DAG1, TNC, COL4A6, GP1BA, ITGB6, ITGA9 |
| mmu05032 | Morphine addiction | 9 | 0.021582369 | GABRB3, GABRB1, GNG2, GABRA4, PDE1A, GNB4, ADCY1, PDE8B, ADCY5 |
| mmu04066 | HIF-1 signaling pathway | 9 | 0.035057542 | CDKN1A, ANGPT2, PFKFB3, ANGPT1, NOS3, TRF, TLR4, EGFR, PDK1 |
| mmu04723 | Retrograde endocannabinoid signaling | 9 | 0.036841276 | GABRB3, GABRB1, GNG2, CNR1, GABRA4, GNB4, ADCY1, COX-2, ADCY5 |
| mmu05412 | Arrhythmogenic right ventricular cardiomyopathy | 8 | 0.011585663 | ITGB1, CACNG7, CACNB3, DAG1, DSG2, CACNA2D4, ITGB6, ITGA9 |
| mmu04727 | GABAergic synapse | 8 | 0.04190812 | GABRB3, GABRB1, GNG2, GABRA4, GNB4, ADCY1, HAP1, ADCY5 |
| mmu00982 | Drug metabolism-cytochrome P450 | 7 | 0.034801983 | ALDH1A3, ADH1, AOX4, GSTO1, UGT2B37, AOX1, UGT2A3 |
| mmu00532 | Glycosaminoglycan biosynthesis | 6 | 0.000661 | CHST7, CHST11, CHST12, CHPF2, CHST15, CHSY3 |
| mmu05217 | Basal cell carcinoma | 6 | 0.048717123 | BMP2, FZD3, FZD2, PTCH1, PTCH2, GLI3 |