Table 3.
The degree values of the top 50 hub genes in GSE33744.
| Gene | Gene title | Score | LogFC |
|---|---|---|---|
| EGFR | Epidermal growth factor receptor | 52 | -1.4 |
| COX-2 | Cyclooxygenase-2 | 34 | 2.019 |
| TLR4 | Toll-like receptor 4 | 31 | 1.361 |
| GNG2 | Guanine nucleotide binding protein (G protein) gamma 2 | 30 | 1.84 |
| GNB4 | Guanine nucleotide binding protein (G protein) beta 4 | 28 | 1.235 |
| ADCY5 | Adenylate cyclase 5 | 22 | 1.038 |
| ADCY1 | Adenylate cyclase 1 | 21 | 1.206 |
| CCL6 | Chemokine (C-C motif) ligand 6 | 21 | 2.879 |
| ITGB1 | Integrin beta 1 | 21 | 1.11 |
| NTRK2 | Neurotrophic tyrosine kinase, receptor, type 2 | 19 | 1.575 |
| IL18 | Interleukin 18 | 19 | 1.324 |
| QSOX1 | Quiescin Q6 sulfhydryl oxidase 1 | 19 | 1.103 |
| HSPA1B | Heat shock protein 1B | 18 | -3.42 |
| ENTPD1 | Ectonucleoside triphosphate diphosphohydrolase 1 | 18 | 1.853 |
| MMP2 | Matrix metallopeptidase 2 | 18 | 1.698 |
| PF4 | Platelet factor 4 | 18 | 2.06 |
| SLCO1A1 | Solute carrier organic anion transporter family, member 1a1 | 16 | -4.82 |
| UGT2B37 | UDP glucuronosyltransferase 2 family, polypeptide B37 | 16 | -1.48 |
| ANGPT1 | Angiopoietin 1 | 16 | -1.12 |
| LPAR1 | Lysophosphatidic acid receptor 1 | 16 | 1.231 |
| KALRN | Kalirin, RhoGEF kinase | 16 | 1.014 |
| CYP4A14 | Cytochrome P450, family 4, subfamily a, polypeptide 14 | 16 | 3.522 |
| ISL1 | ISL LIM Homeobox 1 | 16 | 1.93 |
| NOS3 | Nitric oxide synthase 3 | 16 | 1.159 |
| C5AR1 | Complement component 5a receptor 1 | 16 | 3.044 |
| CP | Veruloplasmin | 16 | 1.134 |
| TRF | Transferrin | 15 | 1.563 |
| PCSK9 | Proprotein convertase subtilisin/kexin type 9 | 15 | -1.68 |
| NES | Nestin | 15 | 1.083 |
| EXO1 | Exonuclease 1 | 15 | 1.913 |
| FBN1 | Fibrillin 1 | 15 | 1.168 |
| UGT2A3 | UDP glucuronosyltransferase 2 family, polypeptide A3 | 14 | -1.95 |
| GPR143 | G protein-coupled receptor 143 | 14 | 1.294 |
| PTGS1 | Prostaglandin-endoperoxide synthase 1 | 14 | 1.212 |
| P2RY14 | Purinergic receptor P2Y, G-protein coupled, 14 | 14 | 1.788 |
| ENPP3 | Ectonucleotide pyrophosphatase/phosphodiesterase 3 | 13 | -1.31 |
| CNR1 | Cannabinoid receptor 1 (brain) | 13 | -1.58 |
| GNA14 | Guanine nucleotide binding protein, alpha 14 | 13 | -1.38 |
| P2RX1 | Purinergic receptor P2X 1 | 13 | 1.223 |
| EDN2 | Endothelin 2 | 13 | 1.312 |
| GRP | Gastrin releasing peptide | 13 | 2.796 |
| CYP2J13 | Cytochrome P450, family 2, subfamily j, polypeptide 13 | 13 | -2.43 |
| TNNT3 | Troponin T3, fast skeletal type | 13 | 3.247 |
| HP | Haptoglobin | 13 | 3.071 |
| BMP2 | Bone morphogenetic protein 2 | 13 | 1.283 |
| SNAI2 | Snail family zinc finger 2 | 13 | 1.057 |
| NEGR1 | Neuronal growth regulator 1 | 13 | -1.84 |
| FSTL1 | Follistatin-like 1 | 13 | 1.575 |
| ADM | Adrenomedullin | 12 | 1.308 |
| ABCB1A | ATP-binding cassette, subfamily B (MDR/TAP), member 1A | 12 | 2.014 |