TABLE 2.
Clinical characterization of systemic biomarkers. Data is presented as the number of patients (n) and percentage of total studied patients (%). Total UI women = 287. Total fertile women = 20
| Clinical characterization | UI women | Fertile women | ||
|---|---|---|---|---|
| n | % | n | % | |
| Anemia | 43 | 15.0 | 1 | 5.0 |
| Hypovitaminosis B and/or D | 210 | 73.2 | 2 | 10.0 |
| Hypothyroidism | 147 | 51.2 | 2 | 10.0 |
| Metabolic syndrome | 161 | 56.1 | 0 | 0 |
| Polycystic ovary syndrome | 53 | 18.5 | 0 | 0 |
| Endometriosis | 78 | 27.2 | 0 | 0 |
| Autoimmunity | 188 | 65.5 | 0 | 0 |
| TPO + | 57 | 19.9 | 0 | 0 |
| TgAb + | 53 | 18.5 | 0 | 0 |
| ANA + | 59 | 20.6 | 0 | 0 |
| ASCA (IgA, IgG) | 88 | 30.7 | 1 | 5.0 |
Abbreviations: Anemia: hemoglobin <12 g/dl; Hypovitaminosis B: Vitamin B12 <200 pg/ml; Hypovitaminosis D: Vitamin D <30 ng/ml; Hypothyroidism: TSH >4 UI/ml; Metabolic syndrome: altered oral glucose tolerance test (OGTT), glycemia >100 mg/dl, insulin >24 mU/L and/or Homeostatic Model Assessment (HOMA) >3; Polycystic ovary syndrome: ultrasound diagnosis and/or inositol-metformin intake; endometriosis: laparoscopic diagnosis and/or CA125 > 35 UI/ml; Autoimmunity: diagnosis of celiac disease, Hashimoto’s disease, Crohn’s disease, autoimmune diabetes, lupus, Graves, rheumatoid arthritis, scleroderma, myasthenia gravis, and/or Sjogren; TPO, Anti-Thyroid Peroxidase; TgAb, Thyroid Antithyroglobulin Antibody; ANA, Anti-nuclear Antibody; ASCA, Anti-Saccharomyces cerevisiae antibodies; IgA, Immunoglobulin A; IgG, Immunoglobulin G.