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. Author manuscript; available in PMC: 2022 Oct 1.
Published in final edited form as: Drug Alcohol Depend. 2021 Jul 28;227:108930. doi: 10.1016/j.drugalcdep.2021.108930

Figure 1.

Figure 1.

Effects of acute morning methamphetamine administration on actigraphy-based sleep parameters. Dose-response curve of the effects of methamphetamine on sleep parameters. Sleep latency (A) and sleep efficiency (B) in the nights after morning (9:00h) administration of vehicle (Veh) or methamphetamine (0.03, 0.1 or 0.3 mg/kg, i.m.) in male rhesus monkeys (N=4). Actigraphy-based sleep-like measures are presented as normalized data (percentage of baseline). Data are normalized sleep parameters for individual monkeys (symbols) and the mean for each sleep parameter (lines). Dotted lines represent baseline sleep parameters (100%). Red-filled symbols represent doses of methamphetamine for which the mean sleep parameters were significantly different from vehicle (Bonferroni t-tests, p<0.05).