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. 2021 Apr 29;29(11):6535–6543. doi: 10.1007/s00520-020-05976-y

Table 1.

Pre- to post-intervention changes in lower-limb volume and symptoms in patients with secondary lymphedema

Outcomes Mean percentage change (95% CI) P
Seated AECT Supine AECT CT P1 P2 P3 Overall P value
Lower-limb volume

1.19% ± 1.32%

(0.62–1.76%)

2.03% ± 1.24%

(1.46–2.60%)

0.99% ± 0.83%

(0.42–1.56%)

1.00 0.01 0.06 0.01
Pain

27.9% ± 53.2%

(8.95–46.87%)

71.0% ± 22.4%

(52.08–89.99%)

45.4% ± 28.8%

(26.44–64.35%)

0.41 0.10 0.02 0.03
Heaviness

27.5% ± 63.6%

(6.34–48.69%)

62.3% ± 26.2%

(41.16–83.51%)

57.6% ± 27.6%

(36.47–78.82%)

0.07 1.00 0.03 0.02

Note. Mean percentage changes in the least square mean (LSM) values were estimated on the basis of analyses of variance using linear mixed-effect modeling. LSM changes in lower limb volume and percentage changes in general symptoms of pain and heaviness were calculated as effects of the intervention.

P1, seated AECT versus CT; P2, supine AECT versus CT; P3, seated AECT versus supine AECT, AECT, active exercise with compression therapy; seated AECT, AECT in a seated position; supine AECT, AECT in a supine position; CT, compression-only therapy