Table 3.
Brain regions showing significant main effects of condition (across groups) for the social vs. random and social help vs. threat contrasts (Z > 2.3, pcorr < 0.05).
| Contrast | Cluster | Nvoxels | pcorr | Max Z | Max Z coordinates (x, y, z) (mm) | AAL regions |
|---|---|---|---|---|---|---|
| Social>random | 1 | 37200 | 0 | 12.40 | (48, −68, −6) | IOG.R, MTG.R, SMG.R, IFGo.R, ANG.R, MOG.R, HIP.R, SFGm.R, REC.L, AMYG.R, TPOm.R |
| 2 | 14173 | 7.26−31 | 11.40 | (−26, −94, −4) | IOG.L, SMG.L, MOG.L | |
| 3 | 4954 | 9.51e−15 | 6.73 | (−22, −6, −20) | TPOm.L | |
| Random>social | 1 | 54149 | 0 | 14.30 | (−12, −94, 22) | CAL.L, CUN.R, HES.R, LING.L, CAL.R, CUN.L, LING.R, PUT.R, SOG.L, ACG.L, MCG.R, INS.L, MCG.L, INS.R, PUT.L |
| Social help>social threat | 1 | 3597 | 7.23e−12 | 5.50 | (−18, −58, 60) | SPG.L, PCUN.L, SPG.R, MOG.L, SOG.L, PCUN.R |
| 2 | 1507 | 3.81e−6 | 4.09 | (28, −6, 52) | SFGd.R, SMA.R, PreCG.R | |
| 3 | 1169 | 5.20e−5 | 5.78 | (−26, −68, −16) | FFG.L, LING.L | |
| 4 | 1019 | 1.79e−4 | 4.84 | (−22, −16, 58) | SFGd.L, PreCG.L | |
| 5 | 532 | 1.67e−2 | 3.97 | (60, −26, 30) | SMG.R, IPL.R | |
| Social threat>social help | 1 | 3421 | 1.94e−11 | 6.33 | (14, −84, 4) | CAL.R, CUN.L, CUN.R, CAL.L, LING.R, SOG.L, PCUN.R, PCUN.L, SOG.R |
| 2 | 1153 | 5.91e−5 | 4.52 | (42, 34, −8) | ORBi.R, IFGt.R, ORBm.R | |
| 3 | 914 | 4.42e−4 | 3.90 | (−32, 28, 0) | ORBi.L, IFGt.L, IFGo.L |
Nvoxels Number of voxels, pcorr corrected p value, Z Z-statistic, AAL Automated Anatomical Labelling atlas, TD typically developing, ASD autism spectrum disorder, ADHD attention-deficit/hyperactivity disorder, R right, L left, IOG inferior occipital gyrus, MTG middle temporal gyrus, SMG supramarginal gyrus, IFGo opercular part of the inferior frontal gyrus, ANG angular gyrus, MOG middle occipital gyrus, HIP hippocampus, SFGm medial superior frontal gyrus, REC gyrus rectus, AMYG amygdala, TPOm pole of the middle temporal gyrus, CAL calcarine fissure and surrounding cortex, CUN cuneus, HES Heschl’s gyrus, LING lingual gyrus, PUT putamen, SOG superior occipital gyrus, ACG anterior cingulate gyrus, MCG middle cingulate gyrus, INS insula, SPG superior parietal gyrus, PCUN precuneus, SFGd dorsolateral superior frontal gyrus, SMA supplemental motor area, PreCG precentral gyrus, FFG fusiform gyrus.