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. Author manuscript; available in PMC: 2022 Oct 1.
Published in final edited form as: Dig Dis Sci. 2021 Mar 26;67(4):1337–1344. doi: 10.1007/s10620-021-06949-9

Table 3.

History of diverticulitis and risk of incident cardiovascular disease among participants with regular screening practices.

Any history of diverticulitis Recent history of diverticulitis within past 4 years Remote history of diverticulitis beyond 4 years
No Yes No Yes No Yes
Number of CVD events 2,001 49 2,001 14 2,001 35
Person-years 445,383 6,294 445,383 1,792 445,383 4,502
Age-adjusted 1 (Ref) 1.69 (1.26-2.27) 1 (Ref) 1.53 (0.89-2.62) 1 (Ref) 1.77 (1.25-2.49)
*Multivariable-adjusted 1 (Ref) 1.56 (1.17-2.09) 1 (Ref) 1.40 (0.82-2.41) 1 (Ref) 1.64 (1.16-2.32)
Full model 1 (Ref) 1.51 (1.13-2.03) 1 (Ref) 1.40 (0.82-2.41) 1 (Ref) 1.56 (1.10-2.20)

Note: Hazard ratio and 95% confidence interval are shown.

*

Adjusted for lifestyle factors (red meat intake, fiber intake, body mass index, calorie intake, smoking, Alternate Healthy Eating Index, alcohol consumption, and physical activity).

Additionally adjusted for family history (myocardial infarction or diabetes), medication (aspirin, NSAID, acetaminophen, lipid-lowering, and anti-hypertensive), hypertension, diabetes, and hyperlipidemia.