Figure 6.

The effect of alisporivir on the content of putative protein components of MPT pore in the skeletal muscle mitochondria. Gene expression of MPT-related proteins measured by real-time PCR: CypD (A), ANT1 (B), ANT2 (C), and α subunit of ATP synthase (D). The data are presented as means ± SEM (n = 10). Data from the Western blot analysis (E). Relative contents of MPT-related proteins, quantification of CypD/tubulin ratio (F), ANT1/tubulin ratio (G), and ANT2/tubulin ratio (H). The data are presented as means ± SEM (n = 5).