Effect of oral administration of CFW on retinal ganglion cell loss after topical exposure to PM2.5 in SD rats. (A) Representative images of cross-sectioned retina with H&E staining (n = 5). Nerve fiber layer (NFL), ganglion cell layer (GCL), inner plexiform layer (IPL), inner nuclear layer (INL), and outer nuclear layer (ONL) are indicated. Scale bar, 50 μm. (B) Thickness of NFL/GCL + IPL layers. (C) The numbers of cells in GCL of 100 μm2 in five different sections were counted. (B,C) The data are expressed as the means ± standard deviation (n = 10). * p < 0.05 and *** p < 0.001 compared to the normal group. ## p < 0.01 and ### p < 0.001 compared to the control group.