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. 2021 Sep 13;26(18):5558. doi: 10.3390/molecules26185558

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Nrf2/ARE signaling is related to the neuroprotective and antioxidant effects mediated by PCs. (a) Knockout efficiency was detected by determination of Nrf2 protein expression using Western blotting; (b) Nrf2/GAPDH protein relative expression (ratio to control); (c) Cell viability; (d) MDA levels; (e) SOD activity. F and p values of the one-way analysis of variance are presented above each chart. The results of Tukey’s post hoc test are presented for selected comparisons: ns, p > 0.05; *, p < 0.05; **, p < 0.01; ***, p < 0.001; the error bars are SD.