Skip to main content
. 2021 Sep 14;11(9):1360. doi: 10.3390/biom11091360
DR diabetic retinopathy
AMD age-related macular degeneration
TGFβ transforming growth factor β
CNS/PNS central and peripheral nervous systems,
BDNF Brain-derived neurotrophic factor
NGF nerve growth factor
NT-3 neurotrophin-3
NT-4/5 neurotrophin-4/5
TrkA–C tropomyosin receptor kinase A–C
p75NTR neurotrophin receptor p75
TGFβR1/2 TGFβ receptor types 1 and 2
BMP bone morphogenetic protein
GDF growth differentiation factors
ALK1/5 activin A receptor like type 1/5
SMAD abbreviation refers to “small worm phenotype” (SMA) and “mother against decapentaplegic” (MAD), which are homologs of C. elegans and drosophila
ECM extracellular matrix
MI myocardial infraction
BAX BCL2 Associated X, Apoptosis Regulator
BCL2 BCL2 Apoptosis Regulator
VEGF vascular endothelial growth factor
CAP capsaicin
GW788388 small-molecule inhibitor of TGFβR1
BRB blood-retinal barrier
BBB blood-brain barrier
RPE retinal pigment epithelium
RGC retinal ganglion cells
CNV choroidal neovascularization
tPA tissue plasminogen activator
NSC neuronal stem cells
t/pMCAO transient or permanent middle cerebral artery occlusion
eNOS endothelial nitric oxide synthase
ENG endoglin