Table 3.

Area under the curve (AUC) of latency profile and effect ratio for the tail-flick tests.

	Normal Saline	Ref. A	L4	L5	L6
AUC (sec × min)	439.8 ± 32.6	512.3 ± 7.2 *	583.0 ± 14.3 **, #	706.1 ± 24.9 **, ##, §§	778.9 ± 26.3 **, ##, §§, †
Effect fold compared to Normal saline	1.00	1.16	1.33	1.61	1.77
Effect fold compared to Ref. A	0.86	1.00	1.14	1.38	1.52

* ANOVA, LSD, p-value < 0.05, compared with normal saline group. ^# ANOVA, LSD, p-value < 0.05, compared with Ref. A group. ^† ANOVA, LSD, p-value < 0.05 compared with L5 group. ** ANOVA, LSD, p-value < 0.005 compared with normal saline group. ^## ANOVA, LSD, p-value < 0.005 compared with Ref. A group. ^§§ ANOVA, LSD, p-value < 0.005 compared with L4 group.